In the Q&A portion of the 09/24/2021 hangout, John answered a question regarding sarcasm.
The webmaster asked whether or not Google is better at understanding sarcasm than it was in the past.
John explained that you should still try to avoid sarcasm, especially on sites like medical sites that fall under the YMYL concept.
If it’s critical information, then make sure that it’s as easy to understand as possible.
This conversation occurs at the 36:41 mark in the video.